Streptomycin Dermatitis in Nurses

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Streptomycin resistance in a streptomycin-producing microorganism.

Cell-free extracts of Streptomyces bikiniensis contain an adenosine 5'-triphosphate-dependent kinase which inactivates streptomycin (Sm) and dihydrostreptomycin by phosphorylation. The products have been identified as streptomycin 6-phosphate and dihydrostreptomycin 6-phosphate. Activity was not present in logarithmic-phase cells, which were susceptible to 25 mug of Sm per ml. In stationary-pha...

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ژورنال

عنوان ژورنال: BMJ

سال: 1958

ISSN: 0959-8138,1468-5833

DOI: 10.1136/bmj.1.5084.1378